![]() 4 Frequently cited goals included aspects of life engagement such as cognitive function (60%), especially memory, and interpersonal aspects of life (57.8%), particularly social engagement. 3Ī survey of patients with MDD found that 42% had goals for treatment. Shared decision making in patients with depression has been shown to improve treatment adherence and patient satisfaction, with no increase in consultation time. Further, involving the patient in planning can augment the sense of agency that is often compromised in people with MDD. In the context of treatment, I like to ask, What is someone doing? How do they like that? And what would they like to be doing?ĭr Thase pointed out that such discussions can provide valuable context regarding the patient’s past level of engagement and functioning. It helps us to understand what they expect from treatment, and then we can consider whether these are realistic goals. It’s always instructive, whether it be for MDD or schizophrenia, to get a sense of a person’s treatment goals. This Academic Highlights, part 3 in a series, summarizes the experts’ discussion of how life engagement can be integrated into patient-centered discussions of treatment goals, as well as how it can inform treatment selection in for those with MDD. In a recent roundtable meeting, a panel of 5 experts discussed life engagement and its relationship to symptoms and functioning in patients with major depressive disorder and schizophrenia. Life engagement encompasses aspects of life experience relating to cognition (including cognition colored by emotion), vitality, motivation and reward, and the ability to feel pleasure. However, patients express that, beyond symptom relief, they have additional goals: restoration of functioning and of the feeling that one can participate in, and engage with, their own life. Addressing these symptoms is clearly a treatment priority, especially in the acute stages of the treatment process. ![]() Outcome measures in major depressive disorder have traditionally focused on characteristic symptoms included in the DSM-5 1 definition of major depressive disorder (MDD): depressed mood, lack of interest or pleasure in activities, fatigue, guilt, and change in weight/appetite. © 2022 Physicians Postgraduate Press, Inc. Patient functioning, life engagement, and treatment goals in major depressive disorder. To cite: Correll CU, Ismail Z, McIntyre RS, et al. Lundbeck A/S and Otsuka Product Development and Commercialization for educational purposes only. The opinions expressed herein are those of the faculty and do not necessarily reflect the views of Healthcare Global Village, Inc., the publisher, or the commercial supporters. The faculty acknowledges Sarah Brownd, MA, ELS, for editorial assistance in developing the manuscript. Lundbeck A/S and Otsuka Product Development and Commercialization. Financial support for preparation and dissemination of this Academic Highlights was provided by H. This evidence-based peer-reviewed Academic Highlights was prepared by Healthcare Global Village, Inc. ![]() ![]() Patient functioning and life engagement: unmet needs in major depressive disorder and schizophrenia. Crescenz Veterans Affairs Medical Center, Philadelphia, Pennsylvania.įinancial disclosures: Please refer to the first Academic Highlights in this series: Correll CU, Ismail Z, McIntyre RS, et al. Thase, MD, Department of Psychiatry, Perelman School of Medicine of the University of Pennsylvania, and the Corporal Michael J. McIntyre, MD, Mood Disorder Psychopharmacology Unit, University Health Network, Department of Psychiatry, University of Toronto Institute of Medical Science, University of Toronto and Departments of Psychiatry and Pharmacology, University of Toronto, Toronto, Ontario, Canada Roueen Rafeyan, MD, Department of Psychiatry, Feinberg School of Medicine, Northwestern University, Chicago, Illinois and Michael E. The faculty were Zahinoor Ismail, MD, Department of Psychiatry, Hotchkiss Brain Institute, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada Roger S. Correll, MD, Zucker School of Medicine at Hofstra/Northwell, Hempstead, New York, and Charité Universitätsmedizin, Berlin, Germany. ![]() The roundtable was chaired by Christoph U. This Academic Highlights section of The Journal of Clinical Psychiatry presents the highlights of the virtual roundtable “Patient Functioning and Life Engagement: Unmet Needs in MDD and Schizophrenia,” which was held May 10, 2022. See more Academic Highlights in this series: Part 1 | Part 2 ![]()
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